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Prof. Dr. Jens Haueisen

Institute Director

Phone +49 3677 69-2860

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TMS - laboratory

Transcranial magnetic stimulation (TMS) is an innovative technology with promising applications in medical diagnosis and therapy of neurological and psychiatric diseases like depression, Parkinson, or schizophrenia. The TMS system installed in the laboratory allows for computer controlled positioning with integrated movement compensation und thus for exact stimulation of patients or probands. The system further allows for neuro-navigation, real-time activity prediction and simultaneous EEG. It consists of four parts:

TMS system:
Magstim, Rapid2 

Magnetic stimulation is possible with single pulses and repetitive pulses. Main parameters are the strength of the magnetic induction (depending on the paradigm and the type of coil up to 0.7 to 3.5T) and the number and frequency (up to 100 Hz) of the impulses). 



Robot system:
Adept, Viper-Roboter s850 

The 6-axis robot is used to position and hold the coil above the patients head. The accuracy is better than 1 mm. 

 

EEG system:
ANT, asa-lab 

The electroencephalography (EEG) system includes up to 256 channels at a sampling rate of 2048 samples per second. The measurements can be done in parallel to the TMS stimulation, which allows for the analysis of the evoked brain activity. 



Navigation system:
ANT, Visor 3D Neuro Navigation 

The core of the navigation system is an infrared camera (NDI Spectra), which allows the recording of the position of reflecting markers and thus the tracking of marked objects with sub-millimeter accuracy. The position of the stimulation coil (and the robot) and the head of the subject are continuously tracked. With the help of this continuous monitoring, head movements of the subject can be followed by the robot. 

Application areas: 

TMS allows for direct stimulation of the brain. This opens up many clinical and research applications areas in the neurosciences. 

Medical diagnosis: The stimulation of the motor cortex produces evoked activity, which can be recorded at the scalp (EEG) and yields motor activity in the periphery (arm, finger, etc.). This motor activity can be assessed with the help of electric recordings and is important for the diagnosis of the diseases influencing the e.g. efferent pathways. 

Therapy: Especially repetitive TMS can enhance or inhibit brain activity. Potential applications are e.g. in the treatment of depression and schizophrenia. 

Research: Currently, we conduct investigations on magnetic stimulation of peripheral nerves and record the resulting somatosensory evoked potentials.