23.12.2021

New publication on the modulation of intraocular pressure

New publication on the modulation of intraocular pressure in humans by the use of a pneumatic system

Figure: Pressure modulator (IOPstim, Imedos Systems GmbH) consisting of the basic unit, the spectacle-like frame and the pressure applicator. The display shows the start screen with top left the right eye (OD) chosen for stimulation (a). Person wearing the spectacle-like frame with the pressure applicator placed at the temporal corner of the open right eye, directly on the conjunctiva. The balloon is connected to the basic unit via tube for pressure modulation (b)

In the publication "Modulation of Human Intraocular Pressure Using a Pneumatic System" we were able to implement a highly accurate and reproducible modulation of intraocular pressure in humans for the first time. For this purpose, we developed a pneumatic modulator in cooperation with Imedos Systems GmbH. In order to increase the intraocular pressure, a small balloon, which is attached to a spectacle frame at the height of the eyelid angle, is inflated. This induces reactions of the blood vessels in the area of the optic nerve head, which are used to determine the pressure conditions in the vessels. In a next step, conclusions can be drawn about pathologically altered regulatory processes of the eye, such as those present in glaucoma. Within the work we could determine the time window in which a reliable determination of the pressure conditions is possible and show basic physiological effects of the pressure modulation.

Benedikt Krauß, Dietmar Link, Richard Stodtmeister, Edgar Nagel, Walthard Vilser, Sascha Klee:
Modulation of Human Intraocular Pressure Using a Pneumatic System. Trans. Vis. Sci. Tech. 2021;10(14):4.


doi: https://doi.org/10.1167/tvst.10.14.4.

Contact:   Dietmar Link
                 Jun.-Prof. Dr.-Ing. Sascha Klee