Technische Universität Ilmenau

Bioorganic Chemistry - Interactive curriculae of TU Ilmenau

The interactive curriculae provide information on the degree programmes offered by the TU Ilmenau.

Please refer to the respective study and examination rules and regulations for the legally binding curricula (Annex Curriculum).

You can find all details on planned lectures and classes in the course catalogue.

Please note that this page is no longer updated. All modules and study plans from PO version 2021 onwards (Bachelor and Master study programs) are now available on the Campus Portal.

module properties Bioorganic Chemistry in degree program Master Biotechnische Chemie 2023
module number200392
examination number2400742
departmentDepartment of Mathematics and Natural Sciences
ID of group 2431 (Nano-Biosystems Engineering)
module leaderProf. Dr. Andreas Schober
term winter term only
languageDeutsch
credit points5
on-campus program (h)45
self-study (h)105
obligationobligatory module
examwritten examination performance, 90 minutes
details of the certificate

Schriftliche Prüfung

link to Moodle course
teacherProf. Schober, PD Dr. Singh
signup details for alternative examinations
maximum number of participants
previous knowledge and experience
learning outcome

Die Studierenden sind fähig, an der Schnittstelle zwischen organischer Chemie und Biotechnologie Probleme zu analysieren, geeignete, insbesondere moderne Laborverfahren zur Lösung der Aufgaben auszuwählen und anhand des Syntheseerfolgs die wissenschaftlichen Ergebnisse  zu bewerten, um schließlich einen geeigneten Syntheseplan vorzulegen. Die Studierenden sind fähig, Aufgaben der chemischen und biologischen Wissenschaft zu analysieren, geeignete Methoden und Synthesepläne auszuwählen und entsprechende Ergebnisse zu gewinnen.

Die Studierenden erarbeiten Problemlösungen komplexer Syntheseaufgaben in der Gruppe. Sie können die von ihnen gewonnen Erkenntnisse gemeinsam in einer Aufgabenstellung analysieren und dokumentieren.

content

This section of the bioorganic chemistry is designed to teach concept of bioconjugation that has regular applications in biotechnology for developing different types of assays, therapies and diagnosis. Students are informed about the role of organic synthesis in biotechnology especially the synthetic chemistry methods those are used for developing biomolecule-drug or substrate conjugates. The major part of this teaching focuses the functional group targets for the biomolecules, biopolymer and biocompatible polymer. Following content is included in this course

  • Application of bioconjugates in medicine and biotechnology
    • Assay and quantification
    • Detection,  tracking,  and  imaging
    • Purification,  capture,  and  scavenging
    • Catalysis  and  chemical modification
    • Therapeutics and  in vivo  diagnostics
    • Vaccines and immune modulation
  • Bioconjugation strategy and design
    • Functional targets of bioconjugation
    • Creating specific functionalities
    • Crosslinkers
    • Fluorescent Probes
    • PEGylation and Synthetic polymers
  • Chemoselective Ligation
    • Bioorthogonal Chemistry
    • Metal-ligand chemistry for bioconjugation
    • (Stept)avidine-Biotin System
media of instruction and technical requirements for education and examination in case of online participationPowerPoint
presentation including some videos from lab experiment in combination with
blackboard teaching is used as Media for information transfer.
literature / referencesBioconjugate techniques by Hermanson by Gerg T. Hermanson
Advances in Biochemical Engineering Biotechnology 125: Biofunctionalization of polymer and their applications by G. S. Nyanhongo, W. Steiner, G. M. Gübitz
Journals: (Included but not limited to)
ACS Chemical Biology (The American Chemical Society)
Bioconjugate Chemistry (The American Chemical Society)
Chemical communication (The Royal Society of Chemistry's Journals)

evaluation of teaching