Publikationen an der Fakultät für Informatik und Automatisierung ab 2015

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Sattler, Kai-Uwe; Herschel, Melanie; Lehner, Wolfgang
Datenbanksysteme für Business, Technologie und Web (BTW 2021) : 13.-17. September 2021 in Dresden, Deutschland. - Bonn : Gesellschaft für Informatik, 2021. - 1 CD-ROM. - (Lecture notes in Informatics (LNI)) ISBN 978-3-88579-705-0
Literaturangaben

Ravi Kumar, Varun; Yogamani, Senthil; Rashed, Hazem; Sitsu, Ganesh; Witt, Christian; Leang, Isabelle; Milz, Stefan; Mäder, Patrick
OmniDet: surround view cameras based multi-task visual perception network for autonomous driving. - In: IEEE Robotics and automation letters, ISSN 2377-3766, Bd. 6 (2021), 2, S. 2830-2837

Surround View fisheye cameras are commonly deployed in automated driving for 360˚ near-field sensing around the vehicle. This work presents a multi-task visual perception network on unrectified fisheye images to enable the vehicle to sense its surrounding environment. It consists of six primary tasks necessary for an autonomous driving system: depth estimation, visual odometry, semantic segmentation, motion segmentation, object detection, and lens soiling detection. We demonstrate that the jointly trained model performs better than the respective single task versions. Our multi-task model has a shared encoder providing a significant computational advantage and has synergized decoders where tasks support each other. We propose a novel camera geometry based adaptation mechanism to encode the fisheye distortion model both at training and inference. This was crucial to enable training on the WoodScape dataset, comprised of data from different parts of the world collected by 12 different cameras mounted on three different cars with different intrinsics and viewpoints. Given that bounding boxes is not a good representation for distorted fisheye images, we also extend object detection to use a polygon with non-uniformly sampled vertices. We additionally evaluate our model on standard automotive datasets, namely KITTI and Cityscapes. We obtain the state-of-the-art results on KITTI for depth estimation and pose estimation tasks and competitive performance on the other tasks. We perform extensive ablation studies on various architecture choices and task weighting methodologies. A short video at https://youtu.be/xbSjZ5OfPes provides qualitative results.



https://doi.org/10.1109/LRA.2021.3062324
Buttgereit, Simon; Roßberg, Michael; Pfeiffer, Michael; Schäfer, Günter
Demo: Leveraging SDN in critical infrastructures. - In: 2021 24th Conference on Innovation in Clouds, Internet and Networks and workshops (ICIN), (2021), S. 86-88

Recent developments in computer networks increased flexibility, making them more dynamic and programmable, e.g., by SDN and NFV. However, this also increased complexity and volatility of network components. This is a challenge for highly regulated environments such as critical infrastructure networks where certified components are used to guarantee security requirements of infrastructures, e.g., through mandatory filtering or encryption of network traffic. This demo paper presents a setup where programmable and volatile components are separated from trusted, and thus certified, components. In particular, programmable Network Operating Systems (NOSes) and SDN controllers are deployed to steer the network flows in a VPN overlay. Yet, these flexible components do not have to be included into a certification process.



https://doi.org/10.1109/ICIN51074.2021.9385545
Huaman, Alex S.; Katzschmann, Michael; Hesse, Steffen; Schäffel, Christoph; Weise, Christoph; Dontsov, Denis; Manske, Eberhard; Reger, Johann
Picometer-scale positioning of a linear drive system via feedforward-feedback control. - In: 2021 IEEE International Conference on Mechatronics (ICM), (2021), insges. 6 S.

This paper deals with the controller design of a linear drive system with potential applications in picometer-scale positioning. The displacement is measured using a high-precision differential plane-mirror laser interferometer. However, this measured signal must be filtered for control purposes and performance validation. For tracing picometers, we adopt a model-based 2-DOF control architecture with a feedforward stage for model-following and a feedback stage for stabilization and compensation of constant disturbances. A straightforward way to deal with noise is to use a feedback controller based on estimated (and filtered) states, which can be generated by a Kalman-Bucy filter. The effectiveness of the presented control strategy is verified via real-time experimentation, where the overall control scheme allows positioning in the picometer level. Moreover, comparative tests in the frequency domain were conducted using the so-called PI-LQR feedback controller based on estimated states.



https://doi.org/10.1109/ICM46511.2021.9385699
Schmitz-Hübsch, Tanja; Lux, Silke; Bauer, Peter; Brandt, Alexander Ulrich; Schlapakow, Elena; Greschus, Susanne; Scheeler, Michael Lothar; Gärtner, Hanna; Kirlangic, Mehmet Eylem; Gras, Vincent; Timmann-Braun, Dagmar; Synofzik, Matthis; Giorgetti, Alejandro; Carloni, Paolo; Shah, Jon N.; Schöls, Ludger; Kopp, Ute; Bußenius, Lisa; Oberwahrenbrock, Timm; Zimmermann, Hanna; Pfueller, Caspar; Kadas, Ella-Maria; Rönnefarth, Maria; Grosch, Anne-Sophie; Endres, Matthias; Amunts, Katrin; Paul, Friedemann; Doss, Sarah; Minnerop, Martina
Spinocerebellar ataxia type 14 : refining clinicogenetic diagnosis in a rare adult-onset disorder. - In: Annals of Clinical and Translational Neurology, ISSN 2328-9503, Bd. 8 (2021), 4, S. 774-789

Objectives Genetic variant classification is a challenge in rare adult-onset disorders as in SCA-PRKCG (prior spinocerebellar ataxia type 14) with mostly private conventional mutations and nonspecific phenotype. We here propose a refined approach for clinicogenetic diagnosis by including protein modeling and provide for confirmed SCA-PRKCG a comprehensive phenotype description from a German multi-center cohort, including standardized 3D MR imaging. Methods This cross-sectional study prospectively obtained neurological, neuropsychological, and brain imaging data in 33 PRKCG variant carriers. Protein modeling was added as a classification criterion in variants of uncertain significance (VUS). Results Our sample included 25 cases confirmed as SCA-PRKCG (14 variants, thereof seven novel variants) and eight carriers of variants assigned as VUS (four variants) or benign/likely benign (two variants). Phenotype in SCA-PRKCG included slowly progressive ataxia (onset at 4-50 years), preceded in some by early-onset nonprogressive symptoms. Ataxia was often combined with action myoclonus, dystonia, or mild cognitive-affective disturbance. Inspection of brain MRI revealed nonprogressive cerebellar atrophy. As a novel finding, a previously not described T2 hyperintense dentate nucleus was seen in all SCA-PRKCG cases but in none of the controls. Interpretation In this largest cohort to date, SCA-PRKCG was characterized as a slowly progressive cerebellar syndrome with some clinical and imaging features suggestive of a developmental disorder. The observed non-ataxia movement disorders and cognitive-affective disturbance may well be attributed to cerebellar pathology. Protein modeling emerged as a valuable diagnostic tool for variant classification and the newly described T2 hyperintense dentate sign could serve as a supportive diagnostic marker of SCA-PRKCG.



https://doi.org/10.1002/acn3.51315
Wells, James; Ortega, Daniel; Steinhoff, Uwe; Dutz, Silvio; Garaio, E.; Sandre, Olivier; Natividad, Eva; Cruz, M. M.; Brero, Francesca; Southern, Paul; Pankhurst, Quentin A.; Spassov, Simo;
Challenges and recommendations for magnetic hyperthermia characterization measurements. - In: International journal of hyperthermia and thermal therapies, ISSN 1464-5157, Bd. 38 (2021), 1, S. 447-460

Purpose The localized heating of magnetic nanoparticles (MNPs) via the application of time-varying magnetic fields - a process known as magnetic field hyperthermia (MFH) - can greatly enhance existing options for cancer treatment; but for broad clinical uptake its optimization, reproducibility and safety must be comprehensively proven. As part of this effort, the quantification of MNP heating - characterized by the specific loss power (SLP), measured in W/g, or by the intrinsic loss power (ILP), in Hm2/kg - is frequently reported. However, in SLP/ILP measurements to date, the apparatus, the analysis techniques and the field conditions used by different researchers have varied greatly, leading to questions as to the reproducibility of the measurements.Materials and Methods An interlaboratory study (across N = 21 European sites) of calorimetry measurements that constitutes a snapshot of the current state-of-the-art within the MFH community has been undertaken. Identical samples of two stable nanoparticle systems were distributed to all participating laboratories. Raw measurement data as well as the results of in-house analysis techniques were collected along with details of the measurement apparatus used. Raw measurement data was further reanalyzed by universal application of the corrected-slope method to examine relative influences of apparatus and results processing.Results The data show that although there is very good intralaboratory repeatability, the overall interlaboratory measurement accuracy is poor, with the consolidated ILP data having standard deviations on the mean of ca. ± 30% to ± 40%. There is a strong systematic component to the uncertainties, and a clear rank correlation between the measuring laboratory and the ILP. Both of these are indications of a current lack of normalization in this field. A number of possible sources of systematic uncertainties are identified, and means determined to alleviate or minimize them. However, no single dominant factor was identified, and significant work remains to ascertain and remove the remaining uncertainty sources.Conclusion We conclude that the study reveals a current lack of harmonization in MFH characterization of MNPs, and highlights the growing need for standardized, quantitative characterization techniques for this emerging medical technology.



https://doi.org/10.1080/02656736.2021.1892837
Schmidt, Helmut; Hahn, Gerald; Deco, Gustavo; Knösche, Thomas R.
Ephaptic coupling in white matter fibre bundles modulates axonal transmission delays. - In: PLoS Computational Biology, ISSN 1553-7358, Bd. 17 (2021), 2, e1007858, S. 1-24

Axonal connections are widely regarded as faithful transmitters of neuronal signals with fixed delays. The reasoning behind this is that extracellular potentials caused by spikes travelling along axons are too small to have an effect on other axons. Here we devise a computational framework that allows us to study the effect of extracellular potentials generated by spike volleys in axonal fibre bundles on axonal transmission delays. We demonstrate that, although the extracellular potentials generated by single spikes are of the order of microvolts, the collective extracellular potential generated by spike volleys can reach several millivolts. As a consequence, the resulting depolarisation of the axonal membranes increases the velocity of spikes, and therefore reduces axonal delays between brain areas. Driving a neural mass model with such spike volleys, we further demonstrate that only ephaptic coupling can explain the reduction of stimulus latencies with increased stimulus intensities, as observed in many psychological experiments.



https://doi.org/10.1371/journal.pcbi.1007858
Dutz, Silvio; Zborowski, Maciej; Häfeli, Urs; Schütt, Wolfgang
Preface to the Special Issue "Scientific and Clinical Applications of Magnetic Carriers". - In: Journal of magnetism and magnetic materials, ISSN 1873-4766, Bd. 525 (2021), 167667

https://doi.org/10.1016/j.jmmm.2020.167667
Schramm, Stefan; Dietzel, Alexander; Blum, Maren-Christina; Link, Dietmar; Klee, Sascha
Light-field imaging of the human optic nerve head at different wavelengths - a case study. - In: Acta ophthalmologica, ISSN 1755-3768, Bd. 99 (2021), S265, insges. 1 S.

https://doi.org/10.1111/j.1755-3768.2020.0140
Schramm, Stefan; Solf, Benjamin; Klee, Sascha
Scatter measurement in the human eye based on a Shack-Hartmann wavefront aberrometer with extended field of view. - In: Acta ophthalmologica, ISSN 1755-3768, Bd. 99 (2021), S265, insges. 1 S.

https://doi.org/10.1111/j.1755-3768.2020.0141