Teaching

The lecture teaches the basics of physical chemistry. Starting from atomic structure and bonding, chemical thermodynamics for near-equilibrium processes is traditionally introduced first, covering terms such as internal energy, reaction enthalpy and chemical potential as well as determination and calculation of formation enthalpies. Phase transitions and their diagrams are discussed for binary systems with different properties. The lecture covers the fundamentals of gas theory, chemical kinetics, and thermally, photo- and electrochemically activated processes. Molecular excited states and the fundamentals of molecular spectroscopy are also discussed. With the discussion of the arrow of time in chemical processes, autocatalysis, bistability, chemical oscillations and structure formation, chemical processes far from equilibrium are introduced and their consequences for inanimate and living nature are explained.

The subject introduces the tasks, methods and instruments of analytics. Subject matter are procedures, devices and functional principles used in qualitative and quantitative analytics as well as for the elucidation of molecular structures. Among other things, the analytical significance of the interaction of substances with electromagnetic radiation from different sections of the spectrum and different methods of analytical spectrometry and spectrophotometry, but also analytical separation techniques such as different chromatographic techniques and mass spectrometry are covered.

Evolution of the universe, star formation, formation of chemical elements, molecules in the universe, organic material in the universe, formation of the earth, role of the second law of thermodynamics in evolution, momentum and self-organization, self-replication, molecular information storage, molecular evolution, molecular aspects of morphogenesis, evolutionary mechanisms.

Colloid science is a branch of physical chemistry. The subject is the physics and chemistry of highly disperse systems. The term "colloid" does not refer to a property of a substance, but to a state of matter. Colloidal particles typically have dimensions in the size range between 1 and 500 nm, which corresponds to about 10³ to10⁹ atoms. This results in large particle surface-to-volume ratios. The properties of colloidal particles are determined by the properties and processes at the particle surfaces. The description of interfacial properties as well as processes at the interface is therefore the focus of the lecture.

Non-equilibrium thermodynamics, reaction mechanisms, kinetics of coupled reactions, dissipative structures, biophysical chemistry, chemical bonds, interface chemistry, amphiphiles and disperse systems, liquid crystals, molecules in alternating electromagnetic fields and molecule spectroscopy, photochemistry (photography and organic photoreactions), excited states and plasma chemistry,electrochemistry (mixed potentials, electrode kinetics and electrochemical basics of etching technology), physicochemical aspects of nanotechnical processes

The lecture deals with the molecular structure of cells, important classes of substances and their role in cellular processes.The students learn the variety of biomolecular composition of cells, cell components and organisms know and acquire expertise in the description of the structure and properties of important classes of biomolecules and their importance for cell biological processes.The composition and spatial structure of natural substances is teached, including proteins, carbohydrates, fats, nucleic acids and selected low molecular weight natural substances with special chemical properties and related functions in the cell and in multicellular organisms.

Physico-chemical basics of technical chemistry, reactor types, operating modes, process scaling, static mixers, thermal reactors, homogeneous and heterogeneous processes in microreactors, material selection for microreactors, miniaturized screenings

Formation of micro- and nanostructures in natural and technical systems, specific advantages and disadvantages of molecular strategies in nanostructure technology;bottom-up strategy;top-down strategy;molecular construction modules;coordination-chemical paths;macro cycles;supermolecular chemistry;disperse systems and interfaces;amphiphiles;molecular self-organization;mono and multifilms;DNA construction technology;connection of molecular techniques with planar technique

The lecture includes the following focal points: general analysis, optical spectroscopy, distribution chromatography, ion chromatography, size exclusion chromatography, coupling between chromatography and mass spectrometer systems (LC-MS), column materials, electrophoresis, isotachophoresis.

The interaction between drugs and the organism, switching on active ingredients, active ingredient target classes / receptors and enzymes, ADME-Tox, pharmacokinetics, pharmacodynamics, lead structure optimization, combinatorial chemistry, assays, active ingredient screening HTS, the development process, examples from different areas of application . The lectures cover general and special pharmaceutical / medicinal chemistry as well as biotechnology. In this context, the basics of drug chemistry (ligand-receptor interactions, qualitative and quantitative structure-activity relationships, computer-aided methods, drug design (structure and function of the most important biological target molecules) are imparted, as well as deeper insights into current drug chemistry using selected substance classes and areas of indication This concerns the chemistry (synthesis, chemical properties) of the active substances concerned, their molecular mechanisms of action and structure-action relationships, the underlying pharmacotherapeutic concepts, desired and important adverse drug effects as well as the biotransformation of medicinal substances