Forschung

Intracellular transport analysis in the cytoplasm

Our goal is to record the processes of active transport in living cells driven by molecular motors using nanoparticle microrheology. The analysis of the data will contribute to the understanding of the underlying processes of intracellular transport.

Topographically controlled 3D cell environments

How do cells explore their immediate three-dimensional environment? How do they distinguish between food and pure surface?

Stem Cell Technology

Stem cells have proven to be a universal tool for tissue regeneration research due to their pluripotency. The ability to control cell differentiation processes by targeted external stimuli will be the basis for adapted 3D cell and tissue models in our field.

Spatially and temporally defined external stimuli on living cells: A chemotactic trap

We developed a microfluidic setup to study the chemotactic response of single cells.

Trapped cells are fixed by alternating stimuli in opposite directions.

This allows cell responses to be studied on very short time scales.

Analysis of cell spreading mechanisms

We investigate actin dynamics during cell spreading on surfaces and the role of membrane proteins in this process.

Control of cells by electrical stimuli

How do cells react to electric fields? Cells can be manipulated in a targeted manner with the aid of tailor-made field courses.