Head of Optoelectrophysiological Engineering

• Investigations of individual color channels of the eye and their processing in the brain
• Objective examinations of the sense of sight
• Pupil oscillation / pupillometry
• EEG recording and EEG signal analysis
• Improvement of EEG recording technique
• Alternative electrode technique / dry electrodes / textile electrodes

• Member of The Association for Research in Vision and Ophthalmology, Inc. (ARVO)
• Member of the European Association for Vision and Eye Research (EVER)
• Member of the Working Committee “Ophthalmic Optic” (AOO)
• Member of the European Society for Microcirculation (ESM)
• Member of the Society for Microcirculation and Vascular Biology (GfMVB)
• Member of the Expert committee "Biosignals - Information Processing in Medicine and Biosciences" of the German Society for Biomedical Engineering (DGBMT/VDE)
• Member of the Prüfungsausschusses im Studiengang Biomedizinsche Technik
• Member of the Kommission für Scientific Integrity und Ethik of the Karl Landsteiner Privatuniversität für Gesundheitswissenschaften

Listed below you will find a selection of important publications. For a complete overview please use the Google Scholar profile.

Publications since the foundation of the department:

Solf, B., Schramm, S., Blum, M.-C., Klee, S.: The Influence of the Stimulus Design on the Harmonic Components of the Steady-State Visual Evoked Potential. Frontiers in Human Neuroscience Bd. 14, Nr. 343. 2020

Solf, B., Blum, M.-C., Klee, S.: Offset characteristic of transient and steady‐state flash visual evoked potentials. Acta Ophthalmologica. 2021;99

Solf, B., Blum, M.-C., Klee, S.: The effect of the stimulus eccentricity on the main component of the steady‐state visual evoked potential. Acta Ophthalmologica. 2021;99

Schramm, S., Solf, B., Klee, S.: Scatter measurement in the human eye based on a Shack‐Hartmann wavefront aberrometer with extended field of view. Acta Ophthalmologica. 2021;99

Schramm, S., Dietzel, A., Blum, M.-C., Link, L., Klee, S.: Light‐Field imaging of the human optic nerve head at different wavelengths—a case study. Acta Ophthalmologica. 2021;99

Prinke, P., Haueisen, J., Klee, S., Rizqie, M. Q., Supriyanto, E., König, K., et al.: Automatic segmentation of skin cells in multiphoton data using multi-stage merging. Sci Rep-Uk. 2021;11(1):1-19

Link, D., Klee, S.: Fundus image quality assessment for an eye model with cataract using adapted illumination patterns. Acta Ophthalmologica. 2021;99

Klee, S., Link, D., Jeager, U.: Relationship between breathing gas mixtures and retinal vessel regulation. Acta Ophthalmologica. 2021;99

Dietzel, A., Schramm, S., Link, D., Klee, S.: Light‐field imaging for glaucoma diagnosis—reproducibility on one patient. Acta Ophthalmologica. 2021;99

Blum, M.-C., Solf, B., Klee, S.: Photopic negative response during and after ocular direct current stimulation. Acta Ophthalmologica. 2021;99

Blum, M.-C., Solf, B., Hunold, A., Klee, S.: Effects of Ocular Direct Current Stimulation on Full Field Electroretinogram. Front Neurosci-Switz. 2021;15:49

Blum, M.-C., Hunold, A., Solf, B., Klee, S.: Ocular direct current stimulation affects retinal ganglion cells. Sci Rep-Uk. 2021;11(1):1-9

Solf, B., Schramm, S., Blum, M.-C., Klee, S.: The influence of the stimulus design on the harmonic components of the steady-state visual evoked potential. Frontiers in human neuroscience. 2020;14:343

Freitag, S., Hunold, A., Klemm, M., Klee, S., Link, D., Nagel, E., et al.: Pulsed Electrical Stimulation of the Human Eye Enhances Retinal Vessel Reaction to Flickering Light (vol 13, 371, 2019). FRONTIERS IN HUMAN NEUROSCIENCE. 2020;14

Freitag, S., Hunold, A., Klemm, M., Klee, S., Link, D., Nagel, E., et al.: Corrigendum: pulsed electrical stimulation of the human eye enhances retinal vessel reaction to flickering light. Frontiers in Human Neuroscience. 2020;14:167

Blum, M.-C., Hunold, A., Solf, B., Klee, S.: The effects of an ocular direct electrical stimulation on pattern-reversal electroretinogram. Front Neurosci-Switz. 2020;14:588

Blum, M.-C., Klee, S.: P44 Combination of a direct current stimulation of the eye and a simultaneous electroretinogram recording. Clinical Neurophysiology. 2020;131(4):e37

Solf, B., Schramm, S., Link, D., Klee, S.: Objective measurement of forward-scattered light in the human eye: An electrophysiological approach. Plos one. 2019;14(4):e0214850

Solf, B., Klee, S.: The effect of stimulus contrast on the harmonic components of steady state visual evoked potentials. Acta Ophthalmologica. 2019;97

Link, D., Klee, S.: Raspberry Pi controlled flicker stimulation in dynamic retinal vessel analysis. Investigative Ophthalmology & Visual Science. 2019;60(9):5733-

Klemm, M., Sauer, L., Klee, S., Link, D., Peters, S., Hammer, M., et al.: Bleaching effects and fluorescence lifetime imaging ophthalmoscopy. Biomed Opt Express. 2019;10(3):1446-61

Klee, S., Link, D.: The effect of different flicker contrasts on the Dynamic Vessel Analysis. Investigative Ophthalmology & Visual Science. 2019;60(9):6081-

Klee, S.: Effects of technical and biological factors on the dynamic vessel analysis. Acta Ophthalmologica. 2019;97

Freitag, S., Hunold, A., Klemm, M., Klee, S., Link, D., Nagel, E., et al.: Pulsed electrical stimulation of the human eye enhances retinal vessel reaction to flickering light. Frontiers in human neuroscience. 2019;13:371

Blum, M.-C., Klee, S.: Validation of a measurement setup for simultaneous ERG recording and ocular current stimulation. Acta Ophthalmologica. 2019;97

Blum, M.-C., Hunold, A., Link, D., Freitag, S., Klee, S.: Amplitude changes in the electrophysiological response of retinal cells during simultaneous current stimulation. Investigative Ophthalmology & Visual Science. 2019;60(9):2504-

Rieger, S., Lüken, L., Link, D., Dutz, S., Klee, S., Baumgarten, D.: Retinal vessel diameter variations and their correlation to arterial blood pressure. Investigative Ophthalmology & Visual Science. 2018;59(9):3198-

Rieger, S., Klee, S., Baumgarten, D.: Experimental characterization and correlation of Mayer waves in retinal vessel diameter and arterial blood pressure. Front Physiol. 2018;9:892

Link, D., Rieger, S., Klee, S.: Dynamic Vessel Analysis using surface-mount device LEDs as light source. Investigative Ophthalmology & Visual Science. 2018;59(9):4695-

Klemm, M., Sauer, L., Klee, S., Link, D., Peters, S., Hammer, M., et al.: Dark-adapted versus bleached state in fluorescence lifetime imaging ophthalmoscopy. Investigative Ophthalmology & Visual Science. 2018;59(9):4661-

Klee, S., Link, D., Sinzinger, S., Haueisen, J.: Scotoma Simulation in Healthy Subjects. Optometry and Vision Science. 2018;95(12):1120-8

Klee, S., Link, D.: The effect of different rest periods on the Dynamic Vessel Analysis. Investigative Ophthalmology & Visual Science. 2018;59(9):4696-

Link, D., Baumgarten, D., Klee, S.: Dynamic retinal vessel analysis using a spatial light modulator for stimulation. Investigative Ophthalmology & Visual Science. 2017;58(8):3131-

Klee, S., Link, D.: The effect of different adaptation conditions on the dynamic vessel analysis. Investigative Ophthalmology & Visual Science. 2017;58(8):3106-

Klee, S., Liebermann, J., Haueisen, J.: Source localization of S-cone and L/M-cone driven signals using silent substitution flash stimulation. Biomedical Engineering/Biomedizinische Technik. 2017;62(3):339-48

Freitag, S., Klee, S., Haueisen, J.: Electrical direct current stimulation affects retinal vessel diameter and vasodilation in healthy subjects. Acta Ophthalmologica. 2017;95

Salchow, C., Strohmeier, D., Klee, S., Jannek, D., Schiecke, K., Witte, H., et al.: Rod driven frequency entrainment and resonance phenomena. Frontiers in human neuroscience. 2016;10:413

Link, D., Klee, S., Freitag, S., Rieger, S., Haueisen, J.: Dynamic Vessel Analysis using LED illumination and stimulation. Investigative Ophthalmology & Visual Science. 2016;57(12):1699-

Klemm, M., Blum, J., Link, D., Klee, S., Haueisen, J., Schweitzer, D.: Improved autofluorescence lifetime ophthalmoscopy image quality based on suppression of the crystalline lens fluorescence. Investigative Ophthalmology & Visual Science. 2016;57(12):1709-

Freitag, S., Hunold, A., Klemm, M., Klee, S., Rieger, S., Link, D., et al.: Anodal direct current stimulation at the eye evokes temporary variations in retinal vessel response to flicker. Investigative Ophthalmology & Visual Science. 2016;57(12):4620-

Baumgarten, D., Rieger, S., Lüken, L., Freitag, S., Link, D., Klee, S.: Correlation of low frequency waves in retinal vessel width and arterial blood pressure. Investigative Ophthalmology & Visual Science. 2016;57(12):4602-