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Tan, Aditya Suryadi; Rabel, Fabian; Sill, Yannick Lee; Sattel, Thomas
A compact 4-DoF MR damper with semi-independent damping adjustment. - In: ACTUATOR 2022: International Conference and Exhibition on New Actuator Systems and Applications, (2022), S. 101-104

Magnetorheological (MR) fluid-based damper systems have been known for their novel property to adjust its damping forces in milliseconds by changing the applied magnetic field strength. This adaptability comes along with a rather simple design compared to classical fluidic damper systems. However, the known operating modes of the MRF, such as shear, flow, squeeze, and pinch mode, are only able to generate damping in one specific direction. On the contrary, vibrations could occur not only in one direction but also in several directions. Therefore, it is desirable to have damping generated not only in one direction but also in several directions. In the worst case, N dampers would need to be installed to dampen vibrations in N translational and rotational directions. In this work, a damper design for a single and compact 4-DoF magnetorheological-based damper is proposed. The compactness is achieved by integrating several control elements to control the MR fluid. It is done by installing five electromagnets in one MR damper without adding any extra fluid chamber so that only one fluid chamber is needed for the damper system. Depending on the direction of the acting vibration, the corresponding electromagnet is then activated accordingly, which changes the state of the MR fluid in the chamber locally. Experimental investigations are conducted and the results are presented in this work. It can be seen from the results, that the design allows the MR damper to possess four degree-of-freedom by using only a single fluid chamber. Moreover, the damping can be adjusted, depending on the damping requirement.



https://ieeexplore.ieee.org/document/9899178
Mühlenhoff, Julian; Körbner, Thorben; Miccoli, Giovanni; Keiner, Dörthe; Hoffmann, Matthias K.; Sauerteig, Philipp; Worthmann, Karl; Flaßkamp, Kathrin; Urbschat, Steffi; Oertel, Joachim; Sattel, Thomas
A manually actuated continuum robot research platform for deployable shape-memory curved cannulae in stereotactic neurosurgery. - In: ACTUATOR 2022: International Conference and Exhibition on New Actuator Systems and Applications, (2022), S. 10-13

In this paper, a research platform for concentric tube continuum robots is developed in order to enable advances in deploying curved cannulae for stereotactic neurosurgery. The system consists of a manually operated high-precision actuation apparatus and a photogrammetric system with measurement errors in the range of 100 micrometer. With this platform, previously planned curved paths can be analyzed ex-situ w.r.t., e.g., target precision, follow-the-leader-behavior, and hysteretic phenomena. Regarding research towards an in-vivo application in human brains, first tests with porcine brain cadavers inside an intraoperative CT are conducted in order to pave the way for histological as well as target reachability studies.



https://ieeexplore.ieee.org/document/9899155
Gao, Xinrui; Shardt, Yuri A. W.
EVOLVE&hahog;INFOMAX: a new criterion for slow feature analysis of nonlinear dynamic system from an information-theoretical perspective. - In: IFAC-PapersOnLine, ISSN 2405-8963, Bd. 55 (2022), 20, S. 43-48

Slow feature analysis (SFA) has attracted much attention as a method for dynamic modelling. However, SFA has an inherent limitation in that it assumes that the dynamic behaviour is linear. In this paper, a new criterion for SFA in general dynamic systems is defined based on the motivation of maximising the information retained during system evolution, which is called EVOLVE&hahog;INFOMAX. The theoretical properties of this new criterion are rigorously justified, the optimisation function under EVOLVE&hahog;INFOMAX is proposed, and a tailored algorithm based on neural networks is designed. The case study on a simulated data set and the Tennessee Eastman process benchmark shows that the proposed method has better performance to extract slow features of nonlinear dynamical systems.



https://doi.org/10.1016/j.ifacol.2022.09.069
Zheng, Niannian; Shardt, Yuri A. W.; Luan, Xiaoli; Liu, Fei
Probabilistic dynamic-controlled latent variable model for pattern-space modelling and pattern-based stochastic model predictive control. - In: IFAC-PapersOnLine, ISSN 2405-8963, Bd. 55 (2022), 7, S. 786-791

Industrial processes are measured and controlled using high-dimensional process variables, but its overall operation is usually characterised by low-dimensional patterns. The changes in the pattern are dominated by three features: free motion, controlled motion, and uncertainty. In this paper, all three features are taken into consideration to propose a new probabilistic dynamic-controlled latent variable (PDCLV) model structure using a dynamic Bayesian network for process modelling in the pattern space. To this end, the linear dynamic system characterised by control inputs is introduced, and the expectation maximisation algorithm is specially designed for learning the PDCLV model. Benefitting from the dynamic causality between control inputs and the explicit modelling of the pattern, a method for pattern-based stochastic model predictive control (SMPC) is implemented successfully to realise process optimisation. A case study on an industrial boiler combustion process demonstrates the benefits of the proposed PDCLV structure for pattern-space modelling and pattern-based SMPC.



https://doi.org/10.1016/j.ifacol.2022.07.540
Ruppert, Holger; Krug, Andreas; Shardt, Yuri A. W.
Method to design a neural network with minimal number of neurons for approximation problems. - In: IFAC-PapersOnLine, ISSN 2405-8963, Bd. 55 (2022), 7, S. 568-573

The widespread use of neural networks to model complex processes requires that a parsimonious model of the process be obtained. One of the main variables in neural networks is the number of neurons in the hidden layer. Selecting an inappropriate number of neurons can lead to over- or underfitting. Therefore, a method is required which determines the appropriate number of neurons in order to approximate a defined system response or time function. This paper presents a proposition to determine the appropriate number of neurons in a feedforward neural network, based on the number of inflection points included in the system response or the time function. The results show that the proposed method has marginal approximation errors (no underfitting) and overfitting can never occur because the minimal number of neurons for the approximation problem is used. To verify the effectiveness of this method, simulations were carried out on a second-order system with and without noise, the Lotka-Volterra equations, and the Runge function.



https://doi.org/10.1016/j.ifacol.2022.07.504
Jahn, Benjamin; Shardt, Yuri A. W.
Modulation-function-based data-driven design of fault detection systems for continuous-time LTI systems. - In: IFAC-PapersOnLine, ISSN 2405-8963, Bd. 55 (2022), 7, S. 562-567

In this paper, a data-driven or model-free approach is presented to design a fault detection system of continuous-time linear time-invariant (LTI) systems based on input and output data in the time domain. The main idea is to directly identify the subspaces and their related matrices relevant for parity-space-based residual generation based on a modulated output equation by use of modulation functions and their properties. Therefore, the explicit model identification of the process for a model-based approach in a conventional two-step procedure can be avoided saving design effort especially for large-scale systems. A simulation of the resulting fault detection system is provided showing the effectiveness of the design approach.



https://doi.org/10.1016/j.ifacol.2022.07.503
Sauerteig, Philipp; Hoffmann, Matthias K.; Mühlenhoff, Julian; Miccoli, Giovanni; Keiner, Dörthe; Urbschat, Steffi; Oertel, Joachim; Sattel, Thomas; Flaßkamp, Kathrin; Worthmann, Karl
Optimal path planning for stereotactic neurosurgery based on an elastostatic cannula model. - In: IFAC-PapersOnLine, ISSN 2405-8963, Bd. 55 (2022), 20, S. 600-605

In this paper, we propose a path-planning problem for stereotactic neurosurgery using concentric tube robots. The main goal is to reach a given region of interest inside the brain, e.g. a tumor, starting from a feasible point on the skull with an ideally short path avoiding certain sensitive brain areas. To describe the shape of the entire cannula from an entry point to the point of interest we use an existing mechanical model for continuum robots. We show numerically that our approach enables the surgeon to reach areas within the brain that would be impossible with a straight cannula as it is currently state of the art.



https://doi.org/10.1016/j.ifacol.2022.09.161
Oppermann, Hannes; Thelen, Antonia; Elliot, Stephen; Zanow, Frank; Haueisen, Jens
A validation study for a consumer-grade auditory-visual stimulation device. - In: Current directions in biomedical engineering, ISSN 2364-5504, Bd. 8 (2022), 2, S. 93-96

Self-care and improving one’s well-being has been growing rapidly in recent years for manifold reasons (e.g. higher workload, corona pandemic). Consumer-grade noninvasive stimulation devices are therefore on the rise to counteract the occurrence of mood disorders and burn-out symptoms. Here, we aim at investigating the impact of dynamically varying auditory-visual stimulation patterns on neural entrainment patterns and resonance phenomena. Twenty-two healthy volunteers (11 female, 25.4 ± 5.1 years, one dropout, seven in control group) participated in the study. EEG data (64 channel; equidistant layout) were acquired preand during stimulation for each volunteer. Visual and auditory stimuli were presented via a headset (ATUM, Neuro- Bright; https://www.neurobright.co.uk/). Presentation patterns (frequency, intensity, spatial distribution) varied within a presentation session but were kept constant across all volunteers. Stimulus intensity was adjusted to individual comfort levels. Individual alpha peak frequencies (iAPF) were calculated via the power spectral density with 50% overlapping 10s epochs from pre-stimulation segments. For both, the study and the control group, a time-frequency representation was calculated for the pre- and during-stimulation segments. From this, power values were determined for different frequency-bands (iAPF, stimulation frequencies and second harmonics of the latter). Statistical analyses focused on contrasting the power values between pre- and during stimulation. Mean iAPF values were 10.25 ± 0.99Hz for the study and 10.63 ± 1.21Hz for the control group respectively. Both, power values at the stimulation frequencies and their second harmonics differed significantly between pre- and during stimulation (p stim =0.001; p harm =0.001) in the study group. No such difference was found for the control group (pstim=0.352; pharm=0.237). Further, neither the study nor the control group showed significant iAPF power differences (p study =0.035; p control =0.352; alpha*=0.008). Our results suggest that lightweight, portable auditory-visual presentation devices represent an effective tool for generating entrainment and resonance effects at home. Further analyses will focus on the investigation of individual differences driving such modulatory effects.



https://doi.org/10.1515/cdbme-2022-1025
Kirlangic, Mehmet Eylem; Yeo, Yi Lin; Fiedler, Patrique; Haueisen, Jens
Simultaneous measurement of DC-EEG and transcutaneous pCO2. - In: Current directions in biomedical engineering, ISSN 2364-5504, Bd. 8 (2022), 2, S. 125-128

DC potential shifts are the shifts observed in the EEG baseline which can last from seconds to minutes. The significance of these low-frequency components in healthy as well as pathological states of human physiology is getting more and more attention not only in scientific research but also in clinical applications. In this paper, we present our novel multimodal measurement setup for simultaneously investigating DC potential shifts in EEG (DC-EEG) and the changes in noninvasive transcutaneous pCO2 measurements. We present preliminary results of our measurements during hyperventilation and apnea, which are two commonly used activation methods for changes in pCO2.



https://doi.org/10.1515/cdbme-2022-1033
Lange, Irene; Prinke, Philipp; Klee, Sascha; Pia¸tek, Łukasz; Warzecha, Marek; König, Karsten; Haueisen, Jens
Feature-based differentiation of malignant melanomas, lesions and healthy skin in multiphoton tomography skin images. - In: Current directions in biomedical engineering, ISSN 2364-5504, Bd. 8 (2022), 2, S. 45-48

https://doi.org/10.1515/cdbme-2022-1013